Aaranya Biosciences Private Limited provides Preclinical Research needs of your discovery program by executing pharmacological and toxicology evaluation of your molecule in a quality, timely and cost-effective manner. Aaranya Biosciences Private Limited, Preclinical Research Facility at Biotech Park, Chennai, Tamil Nadu India. Aaranya Biosciences focus on early discovery, which includes SAR support by screening of compounds for their suitable targets like enzymes, receptors, protein etc by executing in-vitro assays using cell culture and biochemical and enzyme laboratory facility. Assay platform like absorbance, fluorescence, luminescence, imaging which utilizes enzymes, cell line, biological fluids to test their compound activity and rank order their potency. In addition to activity, we test the compound cytotoxicity using cell line, microbes and other biological systems. The compound properties of solubility, dissolution, stability in different pH and simulating fluids are tested to optimize compound nature so that it is effective to show their absorption, metabolism, distribution and excretion in the biological system. In-vivo DMPK studies are done along with screening assays for their activity and toxicity. Execute Pharmacokinetic, pharmacological and toxicity evaluation of compounds are done with its CPCSEA, government of India approved preclinical laboratory animal facility housing rats, mice, rabbits, hamster etc and also zebra fish. The compounds are tested for their efficacy using disease models. Based on the therapeutic area like cardiovascular, neurological disorders, skin and wound infection, metabolic disorders, cancer, disease models are selected, customized and conducted in rats, mice, rabbits, hamster, others and zebrafish. In addition, toxicity and pharmacokinetics studies are executed in rats, mice rabbits and zebra fish along with their organ toxicity and histopathology, clinical serum chemistry, & biomarker measurements. We ensure that the hit and lead drug candidates achieve an optimal balance between ADME, pharmacological and toxicological properties.
Our established objective is to connect people from varied industry segments; collaborate and facilitate to create value to clients through invention, discovery, and commercializing the product/molecule. Aaranya Biosciences Chennai, Tamil Nadu, India with its Preclinical In-vitro and in-vivo platform to conduct research programs leverages on its experienced manpower and state-of-art infrastructure to provide high quality R&D services across biology, DMPK, toxicology and pharmacology. We believe that continuous innovation means to investigate, create, evaluate, activate and celebrate research and discovery services. Clients get a two-way benefit by collaborating with us. Our business models present transparent pricing and an assurance on greater reachability in the market. We offer budget friendly research and discovery services through the latest operational structure and project specific alliances With its preclinical research facility with CPCSEA approved Small laboratory animal facility in Chennai executes efficacy, pharmacokinetics, toxicity & safety studies in Mouse, Rat, Rabbit, Zebrafish. Disease models in the area of neurological diseases (anxiety, depression, addiction Parkinson, Alzheimer, depression, inflammation (arthritis, IBD, NASH etc), ocular diseases, cardiometabolic disorders (obesity, diabetes etc), and cancer.
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Biotechnology Services
We support in herbal extraction, phytochemical analysis, fermentation techniques for isolation of compounds, metabolites and production of enzymes, cell line based specialized cellular assays, fluorescent imaging, staining with DAPI, acridine orange, Propidium iodide etc. Read
Computational Chemistry
We offer computational chemistry & computational biology services to academic and industrial researchers involved in drug discovery and development
Pharmacokinetics and metabolism/excretion study in rats, mice, rabbits and Bioanalysis in plasma, serum, blood, tissues, organs. Biomarker
We provide in-vivo pharmacokinetic study in rats, mice, rabbits and zebra fish, bio-analysis supporting all phases of drug discovery and development.Non-GLP rapid discovery phase pharmacokinetics and bio-analysis for discovery support. Our capabilities include
Preclinical laboratory
Discovery and development programs covering various therapeutic areas including metabolic diseases, oncology, CNS diseases, parkinson, alzheimer, anxiety, locomotor, inflammation, pain, dermatology and infectious diseases which require determination of activity using screening assays, animal studies
Consulting
We can help you with hands-on creation of liquid types or dry types of drug formulations, provide you with access to centers of expertise that provide unique new technologies, assist you with patent and literature
Molecular Pharmacology
We offer the largest array of enzyme assays. We have the expertise to leverage on Cell based specialized assays using cell lines, primary cells to study the cell interactions.
Program Management
We have time tested business models for each pharma and bio industry clients' specific needs in the pharma and life sciences industries. Our flexible and strategic models combine our location advantage and proven competencies. With
DMPK studies (in-vitro, in-vivo)
We offer a full range of in-vivo pharmacokinetic studies for the test compound and identification of metabolites in rodents (rats, mice,rabbits, hamster, guinea pigs, hamster) and zebra fish. we adopt different route of administration
Integrated Discovery Services
We run successful and fully integrated programs for clients at our state-of-art laboratory. Our clients include pharmaceutical companies, biotechnology firms, cosmetics animal health.
Preformulation
From stand-alone discovery support to full development program, we can provide custom and need-specific solutions that include physico-chemical profiling,degration, stability study, optimization of existing formulations, life cycle management and development.
Platform Technologies
We are a drug discovery company with a track record of early drug candidate delivery. By leveraging on innovative proprietary technologies, we could reach the industry average drug discovery timelines of 30%.
Toxicity and Safety Pharmacology
The in vivo preclinical animal facility at Aaranya Biosciences offers a full range of non-GLP safety pharmacology and toxicology evaluations in rats, mice, rabbits and zebra fish. Toxicity study based on acute, subacute and chronic
Disease Models in Rodents and Zebra fish
Vivarium caters to disease model development in rat, mice, rabbits and zebra fish. Laboratory Animal Models Zebra fish Models Experimental Protocol set up, customize study design, monitoring, reporting, data and statistical analysis for Preclinical Studies Animal species: mice, rats,