Medicinal chemistry mostly focuses on small organic molecules includes synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology, enzymology and structural biology, together aiming at the discovery and development of new therapeutic agents.
The synthetic and computational aspects of existing drugs and agents are developed at Aaranya Biosciences in relation to their bioactivities (biological activities and properties), i.e., understanding their structure-activity relationships (SAR).
In early stages of medicinal chemistry development, mainly the isolation of medicinal agents was isolated from plants. Modern technology supports the scientists to create new synthetic drugs.
Chemists and biologists in Aaranya Biosciences work together for a lead on a new drug or doing research on a preclinical drug candidate and then work with toxicologists and pharmacologists.
Drug discovery research is a highly creative and stimulating where people are driven to succeed by personal and scientific objectives, and the desire to contribute to society's well-being.
Medicinal chemists apply their chemistry training to the process of synthesizing on the new pharmaceuticals and improve on the process. They collaborate with other disciplines to use sophisticated analytical techniques to synthesize and test new drug products and to develop the most cost-effective and environmentally friendly means of production.
Medicinal chemists are able to synthesize a vast number of compounds in a relatively short time, a process referred to as combinatorial chemistry where one part of a
Various methods are available like a range of crystallization and distillation procedures to purify and characterize a compound. The process stabilizes the structure, stability of the lead compound.
A suitable validated analytical method is required to support many product chemistry and ecotoxicology tests.
New analytical methods or to transfer existing methodology using a wide range of
In process research and development (PR&D), the identification, production and manipulation of small-molecule drugs ranges from laboratory chemistry to pilot plant manufacture to commercial production.
Variety of disciplines, including